7UR2

Crystal structure of the Sec14 domain of the RhoGEF Kalirin

Summary for 7UR2

• Entry DOI: 10.2210/pdb7ur2/pdb
• Descriptor: Isoform 7 of Kalirin, SULFATE ION (3 entities in total)
• Functional Keywords: ras homologous guanine nucleotide exchange factor, cral-trio domain, spectrin repeat, lysophospholipids, lipid binding protein
• Biological source: Rattus norvegicus (Norway rat)
• Total number of polymer chains: 8
• Total formula weight: 174612.95

Authors

Li, Y.,Doukov, T.I.,Hao, B. (deposition date: 2022-04-21, release date: 2023-01-18)

• Primary citation: Li, Y.,Pustovalova, Y.,Doukov, T.I.,Hoch, J.C.,Mains, R.E.,Eipper, B.A.,Hao, B.; Structure of the Sec14 domain of Kalirin reveals a distinct class of lipid-binding module in RhoGEFs.; Nat Commun, 14:96-96, 2023; PubMed: 36609407; DOI: 10.1038/s41467-022-35678-4

Experimental method

X-RAY DIFFRACTION (1.89 Å)