7UPZ

Structural basis for cell type specific DNA binding of C/EBPbeta: the case of cell cycle inhibitor p15INK4b promoter

Summary for 7UPZ

• Entry DOI: 10.2210/pdb7upz/pdb
• Descriptor: CCAAT/enhancer-binding protein beta, DNA (5'-D(*AP*TP*TP*CP*TP*TP*AP*AP*GP*AP*AP*AP*GP*AP*CP*G)-3'), DNA (5'-D(*TP*CP*GP*TP*CP*TP*TP*TP*CP*TP*TP*AP*AP*GP*AP*A)-3'), ... (4 entities in total)
• Functional Keywords: c/ebpbeta-dna interactions, dna sequence motif, dna binding protein-dna complex, dna binding protein/dna
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 28987.57

Authors

Lountos, G.T.,Cherry, S.,Tropea, J.E.,Wlodawer, A.,Miller, M. (deposition date: 2022-04-18, release date: 2022-11-23, Last modification date: 2023-10-18)

• Primary citation: Lountos, G.T.,Cherry, S.,Tropea, J.E.,Wlodawer, A.,Miller, M.; Structural basis for cell type specific DNA binding of C/EBP beta : The case of cell cycle inhibitor p15INK4b promoter.; J.Struct.Biol., 214:107918-107918, 2022; PubMed: 36343842; DOI: 10.1016/j.jsb.2022.107918

Experimental method

X-RAY DIFFRACTION (2.487 Å)