7UPD

Prefusion-stabilized Nipah virus fusion protein complexed with Fab 2B12

Summary for 7UPD

• Entry DOI: 10.2210/pdb7upd/pdb
• EMDB information: 26662
• Descriptor: Fusion glycoprotein F0, Fab 2B12 heavy chain, Fab 2B12 light chain, ... (4 entities in total)
• Functional Keywords: henipavirus, nipah virus, niv, f, fusion, prefusion, pref, pre-f, neutralizing antibody, fab, viral protein, viral protein-immune system complex, viral protein/immune system
• Biological source: Nipah henipavirus; More
• Total number of polymer chains: 9
• Total formula weight: 249543.06

Authors

Byrne, P.O.,McLellan, J.S. (deposition date: 2022-04-14, release date: 2023-03-29, Last modification date: 2024-01-31)

• Primary citation: Byrne, P.O.,Fisher, B.E.,Ambrozak, D.R.,Blade, E.G.,Tsybovsky, Y.,Graham, B.S.,McLellan, J.S.,Loomis, R.J.; Structural basis for antibody recognition of vulnerable epitopes on Nipah virus F protein.; Nat Commun, 14:1494-1494, 2023; PubMed: 36932063; DOI: 10.1038/s41467-023-36995-y

Experimental method

ELECTRON MICROSCOPY (2.4 Å)