7UHO
Time-Resolved Structure of Metallo Beta-Lactamase L1 in a Complex with Cleaved Moxalactam (500 ms Snapshot)
Summary for 7UHO
Entry DOI | 10.2210/pdb7uho/pdb |
Related | 7L91 |
Descriptor | Putative metallo-beta-lactamase l1 (Beta-lactamase type ii) (Ec 3.5.2.6) (Penicillinase), ZINC ION, (2R)-2-[(R)-carboxy{[(2R)-2-carboxy-2-(4-hydroxyphenyl)acetyl]amino}methoxymethyl]-5-{[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl}-3,6-dihydro-2H-1,3-oxazine-4-carboxylic acid, ... (4 entities in total) |
Functional Keywords | metallo beta lactamase, moxalactam, serial crystallography, structural genomics, center for structural genomics of infectious diseases, hydrolase, csgid |
Biological source | Stenotrophomonas maltophilia K279a |
Total number of polymer chains | 1 |
Total formula weight | 29913.24 |
Authors | Wilamowski, M.,Kim, Y.,Sherrell, D.A.,Lavens, A.,Henning, R.,Maltseva, N.,Endres, M.,Babnigg, G.,Srajer, V.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2022-03-27, release date: 2022-07-13, Last modification date: 2023-10-25) |
Primary citation | Wilamowski, M.,Sherrell, D.A.,Kim, Y.,Lavens, A.,Henning, R.W.,Lazarski, K.,Shigemoto, A.,Endres, M.,Maltseva, N.,Babnigg, G.,Burdette, S.C.,Srajer, V.,Joachimiak, A. Time-resolved beta-lactam cleavage by L1 metallo-beta-lactamase. Nat Commun, 13:7379-7379, 2022 Cited by PubMed: 36450742DOI: 10.1038/s41467-022-35029-3 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
Download full validation report