7U9B

Crystal structure of indoline 7 with KPC-2

Summary for 7U9B

• Entry DOI: 10.2210/pdb7u9b/pdb
• Descriptor: Carbapenem-hydrolyzing beta-lactamase KPC, [(3S)-3-(1H-tetrazol-5-yl)-2,3-dihydro-1H-indol-1-yl][3-(trifluoromethyl)phenyl]methanone (3 entities in total)
• Functional Keywords: beta-lactamase, tetrazole, inhibitor, complex, hydrolase
• Biological source: Klebsiella pneumoniae
• Total number of polymer chains: 1
• Total formula weight: 28809.40

Authors

Akhtar, A.,Chen, Y. (deposition date: 2022-03-10, release date: 2023-03-15, Last modification date: 2023-10-25)

• Primary citation: DeFrees, K.,Cambeis, E.M.,Chen, Y.,Renslo, A.R.; Probing the binding hot spots of KPC-2 carbapenemase using reversible tetrazole-based inhibitors; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.95 Å)