7U8J

Crystal structure of chimeric hemagglutinin cH4/3 in complex with broad protective antibody 31.a.83

Summary for 7U8J

Entry DOI	10.2210/pdb7u8j/pdb
Descriptor	Hemagglutinin HA1 subunit, Hemagglutinin HA2 subunit, Antibody Fab light chain, ... (4 entities in total)
Functional Keywords	universal vaccine design, chimeric influenza hemagglutinin, ha trimer interface and stem, viral protein-immune system complex, viral protein/immune system
Biological source	Influenza A virus More
Total number of polymer chains	4
Total formula weight	104591.69
Authors	Zhu, X.,Wilson, I.A. (deposition date: 2022-03-08, release date: 2022-06-08, Last modification date: 2023-10-18)
Primary citation	Zhu, X.,Han, J.,Sun, W.,Puente-Massaguer, E.,Yu, W.,Palese, P.,Krammer, F.,Ward, A.B.,Wilson, I.A. Influenza chimeric hemagglutinin structures in complex with broadly protective antibodies to the stem and trimer interface. Proc.Natl.Acad.Sci.USA, 119:e2200821119-e2200821119, 2022 Cited by PubMed: 35594401 DOI: 10.1073/pnas.2200821119 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (4.9 Å)

Structure validation