7U75

Human DNA polymerase eta-DNA ternary mismatch complex:reaction with 0.5 mM Mn2+ for 1800s then with 10 mM Mn2+ for 90s

Summary for 7U75

• Entry DOI: 10.2210/pdb7u75/pdb
• Descriptor: DNA polymerase eta, DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ... (7 entities in total)
• Functional Keywords: dna polymerase, transferase, transferase-dna complex, transferase/dna
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 55629.99

Authors

Chang, C.,Gao, Y. (deposition date: 2022-03-07, release date: 2022-05-04, Last modification date: 2023-10-18)

• Primary citation: Chang, C.,Lee Luo, C.,Gao, Y.; In crystallo observation of three metal ion promoted DNA polymerase misincorporation.; Nat Commun, 13:2346-2346, 2022; PubMed: 35487947; DOI: 10.1038/s41467-022-30005-3

Experimental method

X-RAY DIFFRACTION (1.55 Å)