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7U38

Pixantrone tethered DNA duplex

Summary for 7U38
Entry DOI10.2210/pdb7u38/pdb
DescriptorPixantrone AP conjugate-modified DNA, 1,2-ETHANEDIOL (3 entities in total)
Functional Keywordspixantrone, dna structure, pixantrone-ap, pixantrone conjugate, abasic site, dna
Biological sourcesynthetic construct
Total number of polymer chains2
Total formula weight8085.36
Authors
Pallan, P.S.,Egli, M. (deposition date: 2022-02-26, release date: 2023-03-15, Last modification date: 2024-05-22)
Primary citationKellum Jr., A.H.,Pallan, P.S.,Terrell, J.T.,Fu, Y.,Noh, B.,Rizzo, C.J.,Egli, M.,Stone, M.P.
Structural Characterization of a Covalent Conjugate between Pixantrone and an Abasic Site in DNA
To Be Published,
Experimental method
X-RAY DIFFRACTION (2.49 Å)
Structure validation

221051

PDB entries from 2024-06-12

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