7U32

MVV cleaved synaptic complex (CSC) intasome at 3.4 A resolution

Summary for 7U32

Entry DOI	10.2210/pdb7u32/pdb
EMDB information	14453 26322
Descriptor	Integrase, DNA EV273, DNA EV272, ... (5 entities in total)
Functional Keywords	integrase-dna complex, hydrolase, viral protein, viral protein-dna complex, viral protein/dna
Biological source	Visna/maedi virus EV1 KV1772 More
Total number of polymer chains	20
Total formula weight	553198.37
Authors	Shan, Z.,Pye, V.E.,Cherepanov, P.,Lyumkis, D. (deposition date: 2022-02-25, release date: 2022-05-11, Last modification date: 2024-02-21)
Primary citation	Ballandras-Colas, A.,Chivukula, V.,Gruszka, D.T.,Shan, Z.,Singh, P.K.,Pye, V.E.,McLean, R.K.,Bedwell, G.J.,Li, W.,Nans, A.,Cook, N.J.,Fadel, H.J.,Poeschla, E.M.,Griffiths, D.J.,Vargas, J.,Taylor, I.A.,Lyumkis, D.,Yardimci, H.,Engelman, A.N.,Cherepanov, P. Multivalent interactions essential for lentiviral integrase function. Nat Commun, 13:2416-2416, 2022 Cited by PubMed: 35504909 DOI: 10.1038/s41467-022-29928-8 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.46 Å)

Structure validation