7TYX

Human Amylin2 Receptor in complex with Gs and rat amylin peptide

Summary for 7TYX

• Entry DOI: 10.2210/pdb7tyx/pdb
• EMDB information: 26197
• Descriptor: Receptor activity-modifying protein 2, CHOLESTEROL HEMISUCCINATE, amylin peptide, ... (10 entities in total)
• Functional Keywords: amylin receptor, gpcr, ramp2, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 7
• Total formula weight: 191141.24

Authors

Cao, J.,Belousoff, M.J.,Johnson, R.M.,Wootten, D.L.,Sexton, P.M. (deposition date: 2022-02-14, release date: 2022-03-30, Last modification date: 2022-04-06)

• Primary citation: Cao, J.,Belousoff, M.J.,Liang, Y.L.,Johnson, R.M.,Josephs, T.M.,Fletcher, M.M.,Christopoulos, A.,Hay, D.L.,Danev, R.,Wootten, D.,Sexton, P.M.; A structural basis for amylin receptor phenotype.; Science, 375:eabm9609-eabm9609, 2022; PubMed: 35324283; DOI: 10.1126/science.abm9609

Experimental method

ELECTRON MICROSCOPY (2.55 Å)