7TUU
Structure of the SARS-CoV-2 main protease in complex with halicin
Summary for 7TUU
| Entry DOI | 10.2210/pdb7tuu/pdb |
| Descriptor | 3C-like proteinase nsp5, 5-nitro-1,3-thiazole (3 entities in total) |
| Functional Keywords | main protease, viral protein, hydrolase-inhibitor complex, hydrolase/inhibitor |
| Biological source | Severe acute respiratory syndrome coronavirus 2 |
| Total number of polymer chains | 1 |
| Total formula weight | 34215.92 |
| Authors | Yang, K.S.,Liu, W.R. (deposition date: 2022-02-03, release date: 2022-08-03, Last modification date: 2023-10-18) |
| Primary citation | Yang, K.S.,Alex Kuo, S.T.,Blankenship, L.R.,Geng, Z.Z.,Li, S.G.,Russell, D.H.,Yan, X.,Xu, S.,Liu, W.R. Repurposing Halicin as a potent covalent inhibitor for the SARS-CoV-2 main protease. Curr Res Chem Biol, 2:100025-100025, 2022 Cited by PubMed: 35815070DOI: 10.1016/j.crchbi.2022.100025 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.85 Å) |
Structure validation
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