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7TUU

Structure of the SARS-CoV-2 main protease in complex with halicin

Summary for 7TUU
Entry DOI10.2210/pdb7tuu/pdb
Descriptor3C-like proteinase nsp5, 5-nitro-1,3-thiazole (3 entities in total)
Functional Keywordsmain protease, viral protein, hydrolase-inhibitor complex, hydrolase/inhibitor
Biological sourceSevere acute respiratory syndrome coronavirus 2
Total number of polymer chains1
Total formula weight34215.92
Authors
Yang, K.S.,Liu, W.R. (deposition date: 2022-02-03, release date: 2022-08-03, Last modification date: 2023-10-18)
Primary citationYang, K.S.,Alex Kuo, S.T.,Blankenship, L.R.,Geng, Z.Z.,Li, S.G.,Russell, D.H.,Yan, X.,Xu, S.,Liu, W.R.
Repurposing Halicin as a potent covalent inhibitor for the SARS-CoV-2 main protease.
Curr Res Chem Biol, 2:100025-100025, 2022
Cited by
PubMed: 35815070
DOI: 10.1016/j.crchbi.2022.100025
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.85 Å)
Structure validation

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