7TU1

Structure of the L. blandensis dGTPase R37A mutant

Summary for 7TU1

Entry DOI	10.2210/pdb7tu1/pdb
Descriptor	dGTP triphosphohydrolase, 1,2-ETHANEDIOL, SULFATE ION, ... (4 entities in total)
Functional Keywords	dgtpase, nucleotide binding, hydrolase
Biological source	Leeuwenhoekiella blandensis
Total number of polymer chains	3
Total formula weight	158962.15
Authors	Sikkema, A.P.,Klemm, B.P.,Horng, J.C.,Hall, T.M.T. (deposition date: 2022-02-02, release date: 2022-06-01, Last modification date: 2023-10-18)
Primary citation	Klemm, B.P.,Sikkema, A.P.,Hsu, A.L.,Horng, J.C.,Hall, T.M.T.,Borgnia, M.J.,Schaaper, R.M. High-resolution structures of the SAMHD1 dGTPase homolog from Leeuwenhoekiella blandensis reveal a novel mechanism of allosteric activation by dATP. J.Biol.Chem., 298:102073-102073, 2022 Cited by PubMed: 35643313 DOI: 10.1016/j.jbc.2022.102073 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation