7TTW

50S ribosomal subunit from Staphylococcus aureus containing double mutation in uL3 imparting linezolid resistance

Summary for 7TTW

• Entry DOI: 10.2210/pdb7ttw/pdb
• Related: 7TTU
• EMDB information: 26125
• Descriptor: 50S ribosomal protein L19, 50S ribosomal protein L28, 50S ribosomal protein L29, ... (27 entities in total)
• Functional Keywords: 50s subunit, antibiotic resistance, linezolid, ribosome
• Biological source: Staphylococcus aureus; More
• Total number of polymer chains: 27
• Total formula weight: 1307599.65

Authors

Belousoff, M.J.,Piper, S.,Johnson, R. (deposition date: 2022-02-02, release date: 2022-07-06, Last modification date: 2022-09-14)

• Primary citation: Perlaza-Jimenez, L.,Tan, K.S.,Piper, S.J.,Johnson, R.M.,Bamert, R.S.,Stubenrauch, C.J.,Wright, A.,Lupton, D.,Lithgow, T.,Belousoff, M.J.; A Structurally Characterized Staphylococcus aureus Evolutionary Escape Route from Treatment with the Antibiotic Linezolid.; Microbiol Spectr, 10:e0058322-e0058322, 2022; PubMed: 35736238; DOI: 10.1128/spectrum.00583-22

Experimental method

ELECTRON MICROSCOPY (2.9 Å)