7TTO

P450 (OxyA) from kistamicin biosynthesis, mixed heme conformation

Summary for 7TTO

Entry DOI	10.2210/pdb7tto/pdb
Descriptor	cytochrome P450 hydroxylase, PROTOPORPHYRIN IX CONTAINING FE (3 entities in total)
Functional Keywords	cytochrome p450, peptide cyclase, nrps-associated, glycopeptide antibiotic, oxidoreductase
Biological source	Actinomadura parvosata subsp. kistnae
Total number of polymer chains	1
Total formula weight	43394.69
Authors	Greule, A.,Izore, T.,Cryle, M.J. (deposition date: 2022-02-01, release date: 2022-05-11, Last modification date: 2024-04-03)
Primary citation	Greule, A.,Izore, T.,Machell, D.,Hansen, M.H.,Schoppet, M.,De Voss, J.J.,Charkoudian, L.K.,Schittenhelm, R.B.,Harmer, J.R.,Cryle, M.J. The Cytochrome P450 OxyA from the Kistamicin Biosynthesis Cyclization Cascade is Highly Sensitive to Oxidative Damage. Front Chem, 10:868240-868240, 2022 Cited by PubMed: 35464232 DOI: 10.3389/fchem.2022.868240 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.6 Å)

Structure validation