7TQL

CryoEM structure of the human 40S small ribosomal subunit in complex with translation initiation factors eIF1A and eIF5B.

Summary for 7TQL

Entry DOI	10.2210/pdb7tql/pdb
EMDB information	26067
Descriptor	Eukaryotic translation initiation factor 5B, 40S ribosomal protein S7, 40S ribosomal protein S8, ... (40 entities in total)
Functional Keywords	eif5b, translation, initiation, eif1a, ribosome
Biological source	Homo sapiens (human) More
Total number of polymer chains	38
Total formula weight	1234819.23
Authors	Lapointe, C.P.,Grosely, R.,Sokabe, M.,Alvarado, C.,Wang, J.,Montabana, E.,Villa, N.,Shin, B.,Dever, T.,Fraser, C.,Fernandez, I.S.,Puglisi, J.D. (deposition date: 2022-01-26, release date: 2022-04-27, Last modification date: 2022-12-14)
Primary citation	Lapointe, C.P.,Grosely, R.,Sokabe, M.,Alvarado, C.,Wang, J.,Montabana, E.,Villa, N.,Shin, B.S.,Dever, T.E.,Fraser, C.S.,Fernandez, I.S.,Puglisi, J.D. eIF5B and eIF1A reorient initiator tRNA to allow ribosomal subunit joining. Nature, 607:185-190, 2022 Cited by PubMed: 35732735 DOI: 10.1038/s41586-022-04858-z PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.2 Å)

Structure validation