7TOW

Antibody DH1058 Fab fragment bound to SARS-CoV-2 fusion peptide

Summary for 7TOW

Entry DOI	10.2210/pdb7tow/pdb
Descriptor	DH1058 Fab heavy chain, DH1058 Fab Light chain, Spike protein S2, ... (6 entities in total)
Functional Keywords	antibody, fab fragment, immune system, immune system-viral protein complex, immune system/viral protein
Biological source	Homo sapiens More
Total number of polymer chains	6
Total formula weight	104560.34
Authors	Gobeil, S.,Acharya, P. (deposition date: 2022-01-24, release date: 2022-02-16, Last modification date: 2023-10-25)
Primary citation	Gobeil, S.M.,Henderson, R.,Stalls, V.,Janowska, K.,Huang, X.,May, A.,Speakman, M.,Beaudoin, E.,Manne, K.,Li, D.,Parks, R.,Barr, M.,Deyton, M.,Martin, M.,Mansouri, K.,Edwards, R.J.,Eaton, A.,Montefiori, D.C.,Sempowski, G.D.,Saunders, K.O.,Wiehe, K.,Williams, W.,Korber, B.,Haynes, B.F.,Acharya, P. Structural diversity of the SARS-CoV-2 Omicron spike. Mol.Cell, 82:2050-2068.e6, 2022 Cited by PubMed: 35447081 DOI: 10.1016/j.molcel.2022.03.028 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.15 Å)

Structure validation