7TDX
Structure of FOXP3-DNA complex
Summary for 7TDX
Entry DOI | 10.2210/pdb7tdx/pdb |
Descriptor | DNA (5'-D(*AP*AP*AP*TP*TP*TP*GP*TP*TP*TP*AP*CP*TP*C)-3'), DNA (5'-D(P*GP*AP*GP*TP*AP*AP*AP*CP*AP*AP*AP*TP*TP*T)-3'), Forkhead box P3 (3 entities in total) |
Functional Keywords | foxp3, dimer, forkhead, dna, treg, transcription-dna complex, transcription/dna |
Biological source | Mus musculus (house mouse) More |
Total number of polymer chains | 3 |
Total formula weight | 29475.51 |
Authors | |
Primary citation | Leng, F.,Zhang, W.,Ramirez, R.N.,Leon, J.,Zhong, Y.,Hou, L.,Yuki, K.,van der Veeken, J.,Rudensky, A.Y.,Benoist, C.,Hur, S. The transcription factor FoxP3 can fold into two dimerization states with divergent implications for regulatory T cell function and immune homeostasis. Immunity, 55:1354-, 2022 Cited by PubMed: 35926508DOI: 10.1016/j.immuni.2022.07.002 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.1 Å) |
Structure validation
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