7TCQ

Crystal structure of SARS-CoV-2 neutralizing antibody WS6 in complex with spike S2 peptide

Summary for 7TCQ

• Entry DOI: 10.2210/pdb7tcq/pdb
• Descriptor: Anti-SARS-CoV-2 antibody WS6 Fab heavy chain, Anti-SARS-CoV-2 antibody WS6 Fab light chain, Pegylated spike S2 peptide, ... (7 entities in total)
• Functional Keywords: sars-cov-2, spike, antibody, viral protein, viral protein-immune system complex, viral protein/immune system
• Biological source: Mus musculus; More
• Total number of polymer chains: 6
• Total formula weight: 97942.59

Authors

Zhou, T.,Kwong, P.D. (deposition date: 2021-12-28, release date: 2022-08-03, Last modification date: 2023-10-18)

• Primary citation: Shi, W.,Wang, L.,Zhou, T.,Sastry, M.,Yang, E.S.,Zhang, Y.,Chen, M.,Chen, X.,Choe, M.,Creanga, A.,Leung, K.,Olia, A.S.,Pegu, A.,Rawi, R.,Schon, A.,Shen, C.H.,Stancofski, E.D.,Talana, C.A.,Teng, I.T.,Wang, S.,Corbett, K.S.,Tsybovsky, Y.,Mascola, J.R.,Kwong, P.D.; Vaccine-elicited murine antibody WS6 neutralizes diverse beta-coronaviruses by recognizing a helical stem supersite of vulnerability.; Structure, 30:1233-, 2022; PubMed: 35841885; DOI: 10.1016/j.str.2022.06.004

Experimental method

X-RAY DIFFRACTION (2.02 Å)