7TC3
Human APE1 in the apo form
Summary for 7TC3
| Entry DOI | 10.2210/pdb7tc3/pdb |
| Descriptor | DNA-(apurinic or apyrimidinic site) endonuclease, mitochondrial, 1,2-ETHANEDIOL (3 entities in total) |
| Functional Keywords | ap endonuclease1, ape1, hydrolase |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 1 |
| Total formula weight | 32410.83 |
| Authors | Pidugu, L.S.,Pozharski, E.,Drohat, A.C. (deposition date: 2021-12-22, release date: 2022-12-21, Last modification date: 2023-10-25) |
| Primary citation | Pidugu, L.S.,Servius, H.W.,Sevdalis, S.E.,Cook, M.E.,Varney, K.M.,Pozharski, E.,Drohat, A.C. Characterizing inhibitors of human AP endonuclease 1. Plos One, 18:e0280526-e0280526, 2023 Cited by PubMed: 36652434DOI: 10.1371/journal.pone.0280526 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.252 Å) |
Structure validation
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