7TBJ

Composite structure of the human nuclear pore complex (NPC) symmetric core generated with a 12A cryo-ET map of the purified HeLa cell NPC

This is a non-PDB format compatible entry.

Summary for 7TBJ

• Entry DOI: 10.2210/pdb7tbj/pdb
• Related: 1XKS 3CQC 4FHN 4I79 4LIR 4XMM 5C2U 5CWS 5HAX 5HAY 5HB0 5HB1 7MVV 7MVZ 7MW1
• EMDB information: 14322
• Descriptor: NUP155, NUP98 R2, NUP205, ... (30 entities in total)
• Functional Keywords: nuclear pore complex, nucleocytoplasmic transport, alpha-helical solenoid, nuclear pore, transport protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 122
• Total formula weight: 5826209.75

Authors

Petrovic, S.,Samanta, D.,Perriches, T.,Bley, C.J.,Thierbach, K.,Brown, B.,Nie, S.,Mobbs, G.W.,Stevens, T.A.,Liu, X.,Tomaleri, G.P.,Schaus, L.,Hoelz, A. (deposition date: 2021-12-22, release date: 2022-06-22, Last modification date: 2022-06-29)

• Primary citation: Petrovic, S.,Samanta, D.,Perriches, T.,Bley, C.J.,Thierbach, K.,Brown, B.,Nie, S.,Mobbs, G.W.,Stevens, T.A.,Liu, X.,Tomaleri, G.P.,Schaus, L.,Hoelz, A.; Architecture of the linker-scaffold in the nuclear pore.; Science, 376:eabm9798-eabm9798, 2022; PubMed: 35679425; DOI: 10.1126/science.abm9798

Experimental method

ELECTRON MICROSCOPY (23 Å)