7TBA

Pentraxin - ligand complex

Summary for 7TBA

Entry DOI	10.2210/pdb7tba/pdb
Descriptor	C-reactive protein, [3-(dibutylamino)propyl]phosphonic acid, CALCIUM ION (3 entities in total)
Functional Keywords	inflammation, inhibitor, complex, immune system
Biological source	Homo sapiens (human)
Total number of polymer chains	20
Total formula weight	467989.96
Authors	Shing, K.S.C.T.,Morton, C.J.,Parker, M.W. (deposition date: 2021-12-21, release date: 2022-10-19, Last modification date: 2023-10-25)
Primary citation	Zeller, J.,Cheung Tung Shing, K.S.,Nero, T.L.,McFadyen, J.D.,Krippner, G.,Bogner, B.,Kreuzaler, S.,Kiefer, J.,Horner, V.K.,Braig, D.,Danish, H.,Baratchi, S.,Fricke, M.,Wang, X.,Kather, M.G.,Kammerer, B.,Woollard, K.J.,Sharma, P.,Morton, C.J.,Pietersz, G.,Parker, M.W.,Peter, K.,Eisenhardt, S.U. A novel phosphocholine-mimetic inhibits a pro-inflammatory conformational change in C-reactive protein. Embo Mol Med, 15:e16236-e16236, 2023 Cited by PubMed: 36468184 DOI: 10.15252/emmm.202216236 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.5 Å)

Structure validation