7T84
Structure of angiotensin II type I receptor (AT1R) nanobody antagonist AT118i4h32 G26D T57I variant
Summary for 7T84
Entry DOI | 10.2210/pdb7t84/pdb |
Descriptor | Nanobody AT118i4h32 G26D T57I, CITRIC ACID, GLYCEROL, ... (6 entities in total) |
Functional Keywords | single chain antibody fragment, immune system |
Biological source | synthetic construct |
Total number of polymer chains | 8 |
Total formula weight | 116568.55 |
Authors | Nemeth, G.R.,Skiba, M.A.,Kruse, A.C. (deposition date: 2021-12-15, release date: 2022-12-07, Last modification date: 2023-10-25) |
Primary citation | Harvey, E.P.,Shin, J.E.,Skiba, M.A.,Nemeth, G.R.,Hurley, J.D.,Wellner, A.,Shaw, A.Y.,Miranda, V.G.,Min, J.K.,Liu, C.C.,Marks, D.S.,Kruse, A.C. An in silico method to assess antibody fragment polyreactivity. Nat Commun, 13:7554-7554, 2022 Cited by PubMed: 36477674DOI: 10.1038/s41467-022-35276-4 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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