7T5P

Cryo-EM structure of human SIMC1-SLF2 complex

Summary for 7T5P

• Entry DOI: 10.2210/pdb7t5p/pdb
• EMDB information: 25706
• Descriptor: SUMO-interacting motif-containing protein 1, SMC5-SMC6 complex localization factor protein 2 (2 entities in total)
• Functional Keywords: nse5, nse6, smc5, smc6, simc1, slf2, c5orf25, viral restriction, antiviral protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 128889.33

Authors

Maeda, S.,Oravcova, M.,Boddy, M.N.,Otomo, T. (deposition date: 2021-12-13, release date: 2022-12-07)

• Primary citation: Oravcova, M.,Nie, M.,Zilio, N.,Maeda, S.,Jami-Alahmadi, Y.,Lazzerini-Denchi, E.,Wohlschlegel, J.A.,Ulrich, H.D.,Otomo, T.,Boddy, M.; The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.; Elife, 11:-, 2022; PubMed: 36373674; DOI: 10.7554/eLife.79676

Experimental method

ELECTRON MICROSCOPY (3.4 Å)