7T1X

Crystal structure of human Fab A194-01 in complex with its synthetic heptasaccharide Ara6-Man epitope (BSI110888)

This is a non-PDB format compatible entry.

Summary for 7T1X

• Entry DOI: 10.2210/pdb7t1x/pdb
• Descriptor: Fab A194-01 heavy chain, Fab A194-01 light chain, alpha-D-mannopyranose-(1-5)-beta-D-arabinofuranose-(1-2)-alpha-D-arabinofuranose-(1-3)-[beta-D-arabinofuranose-(1-2)-alpha-D-arabinofuranose-(1-5)]alpha-D-arabinofuranose-(1-5)-alpha-D-arabinofuranose, ... (5 entities in total)
• Functional Keywords: ssgcid, tuberculosis infection, diagnostic antibody, a194-01, ara6-man heptasaccharide, lipoarabinomannan, manlam, structural genomics, seattle structural genomics center for infectious disease, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 10
• Total formula weight: 244418.69

Authors

Seattle Structural Genomics Center for Infectious Disease (SSGCID) (deposition date: 2021-12-02, release date: 2022-12-07, Last modification date: 2024-04-03)

• Primary citation: Abendroth, J.,Fox III, D.,Pinter, A.,Choudhary, A.,Honnen, W.J.,Lowary, T.,Horanyi, P.S.,Lorimer, D.D.,Edwards, T.E.; Crystal structure of human Fab A194-01 in complex with its synthetic heptasaccharide Ara6-Man epitope (BSI110888); to be published,

Experimental method

X-RAY DIFFRACTION (2.6 Å)