7SYR

Structure of the wt IRES eIF2-containing 48S initiation complex, closed conformation. Structure 12(wt).

Summary for 7SYR

Entry DOI	10.2210/pdb7syr/pdb
EMDB information	25538
Descriptor	18S rRNA, eS7, eS8, ... (40 entities in total)
Functional Keywords	hcv, ires, 40s, ribosome
Biological source	Homo sapiens (human) More
Total number of polymer chains	39
Total formula weight	1466598.95
Authors	Brown, Z.P.,Abaeva, I.S.,De, S.,Hellen, C.U.T.,Pestova, T.V.,Frank, J. (deposition date: 2021-11-25, release date: 2022-07-27, Last modification date: 2022-08-24)
Primary citation	Brown, Z.P.,Abaeva, I.S.,De, S.,Hellen, C.U.T.,Pestova, T.V.,Frank, J. Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES. Embo J., 41:e110581-e110581, 2022 Cited by PubMed: 35822879 DOI: 10.15252/embj.2022110581 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.6 Å)

Structure validation