7SUD

CryoEM structure of DNA-PK complex VIII

Summary for 7SUD

Entry DOI	10.2210/pdb7sud/pdb
Related	7SU3
EMDB information	25439 25440
Descriptor	DNA-dependent protein kinase catalytic subunit, X-ray repair cross-complementing protein 5, MAGNESIUM ION, ... (4 entities in total)
Functional Keywords	nhej, kinase, dna repair, dna-pk, dna binding protein
Biological source	Homo sapiens (Human) More
Total number of polymer chains	2
Total formula weight	553336.96
Authors	Chen, X.,Liu, L.,Gellert, M.,Yang, W. (deposition date: 2021-11-16, release date: 2022-01-12, Last modification date: 2022-01-19)
Primary citation	Liu, L.,Chen, X.,Li, J.,Wang, H.,Buehl, C.J.,Goff, N.J.,Meek, K.,Yang, W.,Gellert, M. Autophosphorylation transforms DNA-PK from protecting to processing DNA ends. Mol.Cell, 82:177-, 2022 Cited by PubMed: 34936881 DOI: 10.1016/j.molcel.2021.11.025 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.6 Å)

Structure validation