7SMZ

X-ray crystal structure of CYP142A3 from Mycobacterium Marinum in complex with 4-cholesten-3-one

Summary for 7SMZ

• Entry DOI: 10.2210/pdb7smz/pdb
• Descriptor: Cytochrome P450 142A3, (8ALPHA,9BETA)-CHOLEST-4-EN-3-ONE, PROTOPORPHYRIN IX CONTAINING FE, ... (6 entities in total)
• Functional Keywords: substrate bound, oxidoreductase
• Biological source: Mycobacterium marinum
• Total number of polymer chains: 2
• Total formula weight: 93469.37

Authors

Ghith, A.,Bruning, J.B.,Bell, S.G. (deposition date: 2021-10-27, release date: 2022-09-14, Last modification date: 2023-10-18)

• Primary citation: Ghith, A.,Doherty, D.Z.,Bruning, J.B.,Russell, R.A.,De Voss, J.J.,Bell, S.G.; The Structures of the Steroid Binding CYP142 Cytochrome P450 Enzymes from Mycobacterium ulcerans and Mycobacterium marinum.; Acs Infect Dis., 8:1606-1617, 2022; PubMed: 35881654; DOI: 10.1021/acsinfecdis.2c00215

Experimental method

X-RAY DIFFRACTION (2.04 Å)