7SJR

Cryo-EM structure of AdnA-AdnB(W325A) in complex with DNA and AMPPNP

Summary for 7SJR

Entry DOI	10.2210/pdb7sjr/pdb
EMDB information	25164
Descriptor	DNA helicase, DNA (70-MER), MAGNESIUM ION, ... (6 entities in total)
Functional Keywords	homologous recombination, dna end resection, cryoelectron microscopy, dna curtain, dna binding protein, dna binding protein-dna complex, dna binding protein/dna
Biological source	Mycolicibacterium smegmatis (Mycobacterium smegmatis) More
Total number of polymer chains	3
Total formula weight	251403.91
Authors	Wang, J.,Warren, G.M.,Shuman, S.,Patel, D.J. (deposition date: 2021-10-18, release date: 2021-12-22, Last modification date: 2024-06-05)
Primary citation	Warren, G.M.,Meir, A.,Wang, J.,Patel, D.J.,Greene, E.C.,Shuman, S. Structure-activity relationships at a nucleobase-stacking tryptophan required for chemomechanical coupling in the DNA resecting motor-nuclease AdnAB. Nucleic Acids Res., 50:952-961, 2022 Cited by PubMed: 34967418 DOI: 10.1093/nar/gkab1270 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.8 Å)

Structure validation