7SGE

I53-50 nanoparticle core reconstructed from GPC-I53-50NP by focused refinement

Summary for 7SGE

Entry DOI	10.2210/pdb7sge/pdb
EMDB information	25107 25108 25109
Descriptor	Josiah GPCysR4-I53-50A - nanoparticle component, I53-50B component (2 entities in total)
Functional Keywords	glycoprotein, lassa, josiah, vaccine design, nanoparticle, protein design, viral protein
Biological source	synthetic construct More
Total number of polymer chains	2
Total formula weight	92082.45
Authors	Antanasijevic, A.,Brouwer, P.J.M.,Ward, A.B. (deposition date: 2021-10-05, release date: 2022-10-12, Last modification date: 2022-12-28)
Primary citation	Brouwer, P.J.M.,Antanasijevic, A.,Ronk, A.J.,Muller-Krauter, H.,Watanabe, Y.,Claireaux, M.,Perrett, H.R.,Bijl, T.P.L.,Grobben, M.,Umotoy, J.C.,Schriek, A.I.,Burger, J.A.,Tejjani, K.,Lloyd, N.M.,Steijaert, T.H.,van Haaren, M.M.,Sliepen, K.,de Taeye, S.W.,van Gils, M.J.,Crispin, M.,Strecker, T.,Bukreyev, A.,Ward, A.B.,Sanders, R.W. Lassa virus glycoprotein nanoparticles elicit neutralizing antibody responses and protection. Cell Host Microbe, 30:1759-, 2022 Cited by PubMed: 36400021 DOI: 10.1016/j.chom.2022.10.018 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.67 Å)

Structure validation