7SFT

Filamin complex-2

Summary for 7SFT

• Entry DOI: 10.2210/pdb7sft/pdb
• NMR Information: BMRB: 30958
• Descriptor: Filamin-A, Integrin alpha-IIb light chain, form 2 (2 entities in total)
• Functional Keywords: filamin, integrin, inside-out signaling, outside-in signaling, cell adhesion, signaling protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 12344.51

Authors

Liu, J.,Qin, J. (deposition date: 2021-10-04, release date: 2023-04-12, Last modification date: 2023-10-25)

• Primary citation: Liu, J.,Lu, F.,Ithychanda, S.S.,Apostol, M.,Das, M.,Deshpande, G.,Plow, E.F.,Qin, J.; A mechanism of platelet integrin alpha IIb beta 3 outside-in signaling through a novel integrin alpha IIb subunit-filamin-actin linkage.; Blood, 141:2629-2641, 2023; PubMed: 36867840; DOI: 10.1182/blood.2022018333

Experimental method

SOLUTION NMR