7SBW

Structure of OC43 spike in complex with polyclonal Fab5 (Donor 1051)

Summary for 7SBW

• Entry DOI: 10.2210/pdb7sbw/pdb
• EMDB information: 24990
• Descriptor: Human polyclonal Fab model with polyalanine backbone - Heavy chain, Spike protein, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• Functional Keywords: hcov, spike, oc43, polyclonal antibody, empem, viral protein, viral protein-immune system complex, viral protein/immune system
• Biological source: Human coronavirus OC43 (HCoV-OC43); More
• Total number of polymer chains: 5
• Total formula weight: 492008.37

Authors

Bangaru, S.,Antanasijevic, A.,Ward, A. (deposition date: 2021-09-26, release date: 2022-05-04, Last modification date: 2022-05-18)

• Primary citation: Bangaru, S.,Antanasijevic, A.,Kose, N.,Sewall, L.M.,Jackson, A.M.,Suryadevara, N.,Zhan, X.,Torres, J.L.,Copps, J.,de la Pena, A.T.,Crowe Jr., J.E.,Ward, A.B.; Structural mapping of antibody landscapes to human betacoronavirus spike proteins.; Sci Adv, 8:eabn2911-eabn2911, 2022; PubMed: 35507649; DOI: 10.1126/sciadv.abn2911

Experimental method

ELECTRON MICROSCOPY (3.2 Å)