7S2R

nanobody bound to IL-2Rg

Summary for 7S2R

• Entry DOI: 10.2210/pdb7s2r/pdb
• Descriptor: Cytokine receptor common subunit gamma, nanobody gamma-nb6, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
• Functional Keywords: nanobody, cytokine receptor, protein binding
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 45162.35

Authors

Glassman, C.R.,Jude, K.M.,Yen, M.,Garcia, K.C. (deposition date: 2021-09-03, release date: 2022-03-30, Last modification date: 2023-10-18)

• Primary citation: Yen, M.,Ren, J.,Liu, Q.,Glassman, C.R.,Sheahan, T.P.,Picton, L.K.,Moreira, F.R.,Rustagi, A.,Jude, K.M.,Zhao, X.,Blish, C.A.,Baric, R.S.,Su, L.L.,Garcia, K.C.; Facile discovery of surrogate cytokine agonists.; Cell, 185:1414-, 2022; PubMed: 35325595; DOI: 10.1016/j.cell.2022.02.025

Experimental method

X-RAY DIFFRACTION (2.49 Å)