7RWB
AP2 bound to the APA domain of SGIP in the presence of heparin
Summary for 7RWB
Entry DOI | 10.2210/pdb7rwb/pdb |
EMDB information | 24710 24711 24712 24713 |
Descriptor | AP-2 complex subunit alpha-2, AP-2 complex subunit beta, AP-2 complex subunit mu, ... (4 entities in total) |
Functional Keywords | ap2, clathrin vesicle, endocytosis, lipid-binding, adaptor, membrane, transport, muniscin, regulator, sgip1 |
Biological source | Mus musculus (Mouse) More |
Total number of polymer chains | 8 |
Total formula weight | 408583.69 |
Authors | Baker, R.W.,Hollopeter, G.,Partlow, E.A. (deposition date: 2021-08-19, release date: 2022-03-30, Last modification date: 2022-04-27) |
Primary citation | Partlow, E.A.,Cannon, K.S.,Hollopeter, G.,Baker, R.W. Structural basis of an endocytic checkpoint that primes the AP2 clathrin adaptor for cargo internalization. Nat.Struct.Mol.Biol., 29:339-347, 2022 Cited by PubMed: 35347313DOI: 10.1038/s41594-022-00749-z PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.9 Å) |
Structure validation
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