7RUU

Structure of Human ATP:Cobalamin Adenosyltransferase R190C bound to adenosylcobalamin

Summary for 7RUU

Entry DOI	10.2210/pdb7ruu/pdb
Descriptor	Corrinoid adenosyltransferase, ACETATE ION, POTASSIUM ION, ... (6 entities in total)
Functional Keywords	atp:cobalamin adenosyl transferase, cobalamin, vitamin b12, patient mutation, transferase
Biological source	Homo sapiens (Human)
Total number of polymer chains	4
Total formula weight	93405.48
Authors	Mascarenhas, R.,Gouda, H.,Koutmos, M.,Banerjee, R. (deposition date: 2021-08-18, release date: 2021-11-24, Last modification date: 2023-10-18)
Primary citation	Gouda, H.,Mascarenhas, R.,Pillay, S.,Ruetz, M.,Koutmos, M.,Banerjee, R. Patient mutations in human ATP:cob(I)alamin adenosyltransferase differentially affect its catalytic versus chaperone functions. J.Biol.Chem., 297:101373-101373, 2021 Cited by PubMed: 34757128 DOI: 10.1016/j.jbc.2021.101373 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.85 Å)

Structure validation