7RU5
CC6.30 fragment antigen binding in complex with SARS-CoV-2-6P-Mut7 S protein (non-uniform refinement)
Summary for 7RU5
Entry DOI | 10.2210/pdb7ru5/pdb |
EMDB information | 24697 |
Descriptor | Spike glycoprotein, CC6.30 Fab heavy chain Fv, CC6.30 Fab kappa chain Fv, ... (5 entities in total) |
Functional Keywords | covid, sars-cov-2, stabilizing mutations, neutralizing antibody, rbd, viral protein, viral protein-immune system complex, viral protein/immune system |
Biological source | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2) More |
Total number of polymer chains | 7 |
Total formula weight | 483197.59 |
Authors | Ozorowski, G.,Turner, H.L.,Ward, A.B. (deposition date: 2021-08-16, release date: 2022-08-24, Last modification date: 2024-01-17) |
Primary citation | Zhao, F.,Keating, C.,Ozorowski, G.,Shaabani, N.,Francino-Urdaniz, I.M.,Barman, S.,Limbo, O.,Burns, A.,Zhou, P.,Ricciardi, M.J.,Woehl, J.,Tran, Q.,Turner, H.L.,Peng, L.,Huang, D.,Nemazee, D.,Andrabi, R.,Sok, D.,Teijaro, J.R.,Whitehead, T.A.,Ward, A.B.,Burton, D.R.,Jardine, J.G. Engineering SARS-CoV-2 neutralizing antibodies for increased potency and reduced viral escape pathways. Iscience, 25:104914-104914, 2022 Cited by PubMed: 35971553DOI: 10.1016/j.isci.2022.104914 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.6 Å) |
Structure validation
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