7REO

Crystal structure of an engineered variant of single-chain Penicillin G Acylase from Kluyvera cryocrescens (global hydrolysis Rd3CHis)

Summary for 7REO

Entry DOI	10.2210/pdb7reo/pdb
Descriptor	Penicillin G Acylase, CALCIUM ION (3 entities in total)
Functional Keywords	penicillin, acylase, hydrolase
Biological source	Kluyvera cryocrescens
Total number of polymer chains	1
Total formula weight	86206.26
Authors	Orth, P. (deposition date: 2021-07-13, release date: 2021-11-17, Last modification date: 2023-10-18)
Primary citation	Fryszkowska, A.,An, C.,Alvizo, O.,Banerjee, G.,Canada, K.A.,Cao, Y.,DeMong, D.,Devine, P.N.,Duan, D.,Elgart, D.M.,Farasat, I.,Gauthier, D.R.,Guidry, E.N.,Jia, X.,Kong, J.,Kruse, N.,Lexa, K.W.,Makarov, A.A.,Mann, B.F.,Milczek, E.M.,Mitchell, V.,Nazor, J.,Neri, C.,Orr, R.K.,Orth, P.,Phillips, E.M.,Riggins, J.N.,Schafer, W.A.,Silverman, S.M.,Strulson, C.A.,Subramanian, N.,Voladri, R.,Yang, H.,Yang, J.,Yi, X.,Zhang, X.,Zhong, W. A chemoenzymatic strategy for site-selective functionalization of native peptides and proteins. Science, 376:1321-1327, 2022 Cited by PubMed: 35709255 DOI: 10.1126/science.abn2009 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.812 Å)

Structure validation