7RCB
Crystal Structure of a PMS2 VUS
Summary for 7RCB
| Entry DOI | 10.2210/pdb7rcb/pdb |
| Descriptor | Mismatch repair endonuclease PMS2 (2 entities in total) |
| Functional Keywords | mismatch repair, variant of uncertain significance, atpase domain, dna repair enzyme, hydrolase |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 2 |
| Total formula weight | 80972.41 |
| Authors | D'Arcy, B.M.,Prakash, A. (deposition date: 2021-07-07, release date: 2022-03-02, Last modification date: 2023-10-25) |
| Primary citation | D'Arcy, B.M.,Arrington, J.,Weisman, J.,McClellan, S.B.,Yang, Z.,Deivanayagam, C.,Blount, J.,Prakash, A. PMS2 variant results in loss of ATPase activity without compromising mismatch repair. Mol Genet Genomic Med, 10:e1908-e1908, 2022 Cited by PubMed: 35189042DOI: 10.1002/mgg3.1908 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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