7R6O

Pyrrolysyl-tRNA synthetase from methanogenic archaeon ISO4-G1 (G1PylRS)

Summary for 7R6O

Entry DOI	10.2210/pdb7r6o/pdb
Descriptor	Pyrrolysyl-tRNA synthetase PylS, 1,2-ETHANEDIOL, SULFATE ION, ... (4 entities in total)
Functional Keywords	trna synthetases, trna-ligase, trna synthetases class ii, translation
Biological source	methanogenic archaeon mixed culture ISO4-G1
Total number of polymer chains	4
Total formula weight	123854.60
Authors	Frkic, R.L.,Huber, T.,Jackson, C.J. (deposition date: 2021-06-23, release date: 2022-03-02, Last modification date: 2023-10-18)
Primary citation	Abdelkader, E.H.,Qianzhu, H.,George, J.,Frkic, R.L.,Jackson, C.J.,Nitsche, C.,Otting, G.,Huber, T. Genetic Encoding of Cyanopyridylalanine for In-Cell Protein Macrocyclization by the Nitrile-Aminothiol Click Reaction. Angew.Chem.Int.Ed.Engl., 61:e202114154-e202114154, 2022 Cited by PubMed: 35102680 DOI: 10.1002/anie.202114154 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation