7QT5

Room temperature In-situ SARS-CoV-2 MPRO with bound Z31792168

Summary for 7QT5

Entry DOI	10.2210/pdb7qt5/pdb
Descriptor	3C-like proteinase nsp5, 2-cyclohexyl-~{N}-pyridin-3-yl-ethanamide, DIMETHYL SULFOXIDE, ... (4 entities in total)
Functional Keywords	protease, main protease, sars-cov-2, viral protein
Biological source	Severe acute respiratory syndrome coronavirus 2
Total number of polymer chains	1
Total formula weight	33993.85
Authors	Horrell, S.,Gildae, R.J.,Axford, D.,Owen, C.D.,Lukacik, P.,Strain-Damerell, C.,Owen, R.L.,Walsh, M.A. (deposition date: 2022-01-14, release date: 2022-05-04, Last modification date: 2024-01-31)
Primary citation	Gildea, R.J.,Beilsten-Edmands, J.,Axford, D.,Horrell, S.,Aller, P.,Sandy, J.,Sanchez-Weatherby, J.,Owen, C.D.,Lukacik, P.,Strain-Damerell, C.,Owen, R.L.,Walsh, M.A.,Winter, G. xia2.multiplex: a multi-crystal data-analysis pipeline. Acta Crystallogr D Struct Biol, 78:752-769, 2022 Cited by PubMed: 35647922 DOI: 10.1107/S2059798322004399 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.26 Å)

Structure validation