7QJL
Crystal structure of CYP142 from Mycobacterium tuberculosis in complex with an inhibitor
Summary for 7QJL
| Entry DOI | 10.2210/pdb7qjl/pdb |
| Related | 7QWN |
| Descriptor | Steroid C26-monooxygenase, PROTOPORPHYRIN IX CONTAINING FE, ACETATE ION, ... (6 entities in total) |
| Functional Keywords | cyp, p450, complex, inhibitor, tb, tuberculosis, cholesterol, cytochrome, heme, oxidoreductase |
| Biological source | Mycobacterium tuberculosis |
| Total number of polymer chains | 1 |
| Total formula weight | 45632.68 |
| Authors | Snee, M.,Levy, C.,Katariya, M. (deposition date: 2021-12-16, release date: 2022-12-28, Last modification date: 2024-02-07) |
| Primary citation | Katariya, M.M.,Snee, M.,Tunnicliffe, R.B.,Kavanagh, M.E.,Boshoff, H.I.M.,Amadi, C.N.,Levy, C.W.,Munro, A.W.,Abell, C.,Leys, D.,Coyne, A.G.,McLean, K.J. Structure Based Discovery of Inhibitors of CYP125 and CYP142 from Mycobacterium tuberculosis. Chemistry, 29:e202203868-e202203868, 2023 Cited by PubMed: 36912255DOI: 10.1002/chem.202203868 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.38 Å) |
Structure validation
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