7QHZ
Crystal structure of KLK6 in complex with compound DKFZ917
Summary for 7QHZ
Entry DOI | 10.2210/pdb7qhz/pdb |
Descriptor | Kallikrein-6, (5~{R})-3-(4-carbamimidoylphenyl)-~{N}-[(1~{S})-1-naphthalen-1-ylpropyl]-2-oxidanylidene-1,3-oxazolidine-5-carboxamide, GLYCEROL, ... (4 entities in total) |
Functional Keywords | serine proteases, peptide binding protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 24926.26 |
Authors | Jagtap, P.K.A.,Baumann, A.,Lohbeck, J.,Isak, D.,Miller, A.,Hennig, J. (deposition date: 2021-12-14, release date: 2022-11-23, Last modification date: 2024-01-31) |
Primary citation | Baumann, A.,Isak, D.,Lohbeck, J.,Jagtap, P.K.A.,Hennig, J.,Miller, A.K. Scalable synthesis and structural characterization of reversible KLK6 inhibitors. Rsc Adv, 12:26989-26993, 2022 Cited by PubMed: 36320846DOI: 10.1039/d2ra04670a PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.5 Å) |
Structure validation
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