7QHS

S. cerevisiae CMGE nucleating origin DNA melting

This is a non-PDB format compatible entry.

Summary for 7QHS

• Entry DOI: 10.2210/pdb7qhs/pdb
• EMDB information: 13978 13988
• Descriptor: DNA replication licensing factor MCM2, Cell division control protein 45, DNA polymerase epsilon subunit B, ... (19 entities in total)
• Functional Keywords: dna replication, helicase, initiation, dna origin, replication
• Biological source: Saccharomyces cerevisiae (baker's yeast); More
• Total number of polymer chains: 15
• Total formula weight: 1148414.47

Authors

Lewis, J.S.,Sousa, J.S.,Costa, A. (deposition date: 2021-12-14, release date: 2022-06-15, Last modification date: 2022-07-06)

• Primary citation: Lewis, J.S.,Gross, M.H.,Sousa, J.,Henrikus, S.S.,Greiwe, J.F.,Nans, A.,Diffley, J.F.X.,Costa, A.; Mechanism of replication origin melting nucleated by CMG helicase assembly.; Nature, 606:1007-1014, 2022; PubMed: 35705812; DOI: 10.1038/s41586-022-04829-4

Experimental method

ELECTRON MICROSCOPY (3.3 Å)