7Q1W

Ruminococcus gnavus ATC29149 endo-beta-1,4-galactosidase (RgGH98) E411A in complex with blood group A (BgA II) tetrasaccharide

This is a non-PDB format compatible entry.

Summary for 7Q1W

• Entry DOI: 10.2210/pdb7q1w/pdb
• Descriptor: Ruminococcus gnavus end galactosidase GH98, alpha-L-fucopyranose-(1-2)-[2-acetamido-2-deoxy-alpha-D-galactopyranose-(1-3)]beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... (7 entities in total)
• Functional Keywords: endogalactosidase, glycoside hydrolase, hydrolase
• Biological source: Ruminococcus gnavus (strain ATCC 29149 / VPI C7-9)
• Total number of polymer chains: 1
• Total formula weight: 96344.76

Authors

Owen, C.D.,Wu, H.,Crost, E.H.,van Bakel, W.,Gascuena, A.M.,Latousakis, D.,Hicks, T.,Walpole, S.,Urbanowicz, P.A.,Ndeh, D.,Monaco, S.,Salom, L.S.,Griffiths, R.,Colvile, A.,Spencer, D.I.R.,Walsh, M.A.,Angulo, J.,Juge, N. (deposition date: 2021-10-21, release date: 2022-03-16, Last modification date: 2024-01-31)

• Primary citation: Wu, H.,Crost, E.H.,Owen, C.D.,van Bakel, W.,Martinez Gascuena, A.,Latousakis, D.,Hicks, T.,Walpole, S.,Urbanowicz, P.A.,Ndeh, D.,Monaco, S.,Sanchez Salom, L.,Griffiths, R.,Reynolds, R.S.,Colvile, A.,Spencer, D.I.R.,Walsh, M.,Angulo, J.,Juge, N.; The human gut symbiont Ruminococcus gnavus shows specificity to blood group A antigen during mucin glycan foraging: Implication for niche colonisation in the gastrointestinal tract.; Plos Biol., 19:e3001498-e3001498, 2021; PubMed: 34936658; DOI: 10.1371/journal.pbio.3001498

Experimental method

X-RAY DIFFRACTION (1.65 Å)