7PRS

Crystal Structure of the B subunit of heat labile enterotoxin LT-IIc from Escherichia coli in complex with Sialyl-lacto-N-neotetraose d

This is a non-PDB format compatible entry.

Summary for 7PRS

• Entry DOI: 10.2210/pdb7prs/pdb
• Related: 7PRP
• Descriptor: Heat-labile enterotoxin IIA, B chain, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose, ... (7 entities in total)
• Functional Keywords: lectin, ganglioside, heat labile enterotoxin, sugar binding protein
• Biological source: Escherichia coli
• Total number of polymer chains: 10
• Total formula weight: 119968.30

Authors

Varrot, A. (deposition date: 2021-09-22, release date: 2022-02-02, Last modification date: 2024-01-31)

• Primary citation: Zalem, D.,Juhas, M.,Terrinoni, M.,King-Lyons, N.,Lebens, M.,Varrot, A.,Connell, T.D.,Teneberg, S.; Characterization of the ganglioside recognition profile of Escherichia coli heat-labile enterotoxin LT-IIc.; Glycobiology, 32:391-403, 2022; PubMed: 34972864; DOI: 10.1093/glycob/cwab133

Experimental method

X-RAY DIFFRACTION (2 Å)