7PHV
PfCyRPA bound to monoclonal antibody Cy.007 Fab fragment
Summary for 7PHV
| Entry DOI | 10.2210/pdb7phv/pdb |
| Descriptor | Cysteine-rich protective antigen, Monoclonal antibody Cy.007 heavy chain, Monoclonal antibody Cy.007 light chain, ... (4 entities in total) |
| Functional Keywords | malaria, plasmodium falciparum, monoclonal antibody, vaccine, immune system |
| Biological source | Plasmodium falciparum 3D7 More |
| Total number of polymer chains | 6 |
| Total formula weight | 173961.76 |
| Authors | Ragotte, R.J.,Higgins, M.K. (deposition date: 2021-08-18, release date: 2022-02-09, Last modification date: 2024-01-31) |
| Primary citation | Ragotte, R.J.,Pulido, D.,Lias, A.M.,Quinkert, D.,Alanine, D.G.W.,Jamwal, A.,Davies, H.,Nacer, A.,Lowe, E.D.,Grime, G.W.,Illingworth, J.J.,Donat, R.F.,Garman, E.F.,Bowyer, P.W.,Higgins, M.K.,Draper, S.J. Heterotypic interactions drive antibody synergy against a malaria vaccine candidate. Nat Commun, 13:933-933, 2022 Cited by PubMed: 35177602DOI: 10.1038/s41467-022-28601-4 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3.091 Å) |
Structure validation
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