7PEA

cryo-EM structure of DEPTOR bound to human mTOR complex 1, overall refinement

Summary for 7PEA

• Entry DOI: 10.2210/pdb7pea/pdb
• EMDB information: 13350
• Descriptor: Serine/threonine-protein kinase mTOR, Target of rapamycin complex subunit LST8, Regulatory-associated protein of mTOR, ... (5 entities in total)
• Functional Keywords: deptor, mtor, regulator, inhibitor, mtorc1, dep-domain, pdz-domain, signaling protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 8
• Total formula weight: 1052766.41

Authors

Waelchli, M.,Maier, T. (deposition date: 2021-08-09, release date: 2021-09-08, Last modification date: 2021-09-29)

• Primary citation: Walchli, M.,Berneiser, K.,Mangia, F.,Imseng, S.,Craigie, L.M.,Stuttfeld, E.,Hall, M.N.,Maier, T.; Regulation of human mTOR complexes by DEPTOR.; Elife, 10:-, 2021; PubMed: 34519268; DOI: 10.7554/eLife.70871

Experimental method

ELECTRON MICROSCOPY (4.07 Å)