7PB1

Structure of the human heterotetrameric cis-prenyltransferase complex in complex with magnesium, GGPP and IsPP

Summary for 7PB1

• Entry DOI: 10.2210/pdb7pb1/pdb
• Related: 7PAX 7PAY 7PB0
• Descriptor: Dehydrodolichyl diphosphate synthase complex subunit DHDDS, Dehydrodolichyl diphosphate synthase complex subunit NUS1, MAGNESIUM ION, ... (6 entities in total)
• Functional Keywords: dhdds, ngbr, hcit, cis-prenyltransferase, dolichol, transferase
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 64150.47

Authors

Giladi, M.,Lisnyansky Bar-El, M.,Haitin, Y. (deposition date: 2021-07-30, release date: 2022-06-01, Last modification date: 2024-01-31)

• Primary citation: Giladi, M.,Lisnyansky Bar-El, M.,Vankova, P.,Ferofontov, A.,Melvin, E.,Alkaderi, S.,Kavan, D.,Redko, B.,Haimov, E.,Wiener, R.,Man, P.,Haitin, Y.; Structural basis for long-chain isoprenoid synthesis by cis -prenyltransferases.; Sci Adv, 8:eabn1171-eabn1171, 2022; PubMed: 35584224; DOI: 10.1126/sciadv.abn1171

Experimental method

X-RAY DIFFRACTION (2.59 Å)