7P7H

Crystal structure of Casein Kinase I delta (CK1d) with alphaG-in conformation

Summary for 7P7H

Entry DOI	10.2210/pdb7p7h/pdb
Descriptor	Casein kinase I isoform delta, ADENOSINE MONOPHOSPHATE (3 entities in total)
Functional Keywords	casein kinase, ck1d, csnk1d, conformation plasticity, alpha g, activation segment., structural genomics, structural genomics consortium, sgc, transferase
Biological source	Homo sapiens (Human)
Total number of polymer chains	2
Total formula weight	69544.05
Authors	Chaikuad, A.,Zhubi, R.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2021-07-19, release date: 2022-04-13, Last modification date: 2024-01-31)
Primary citation	Cullati, S.N.,Chaikuad, A.,Chen, J.S.,Gebel, J.,Tesmer, L.,Zhubi, R.,Navarrete-Perea, J.,Guillen, R.X.,Gygi, S.P.,Hummer, G.,Dotsch, V.,Knapp, S.,Gould, K.L. Kinase domain autophosphorylation rewires the activity and substrate specificity of CK1 enzymes. Mol.Cell, 82:2006-, 2022 Cited by PubMed: 35353987 DOI: 10.1016/j.molcel.2022.03.005 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation