7P7G

Crystal structure of phosphorylated pT220 Casein Kinase I delta (CK1d), conformation 2 and 3

Summary for 7P7G

• Entry DOI: 10.2210/pdb7p7g/pdb
• Descriptor: Casein kinase I isoform delta, CITRIC ACID, 1,2-ETHANEDIOL, ... (5 entities in total)
• Functional Keywords: casein kinase, ck1d, csnk1d, conformation plasticity, alpha g, activation segment, phosphorylation., structural genomics, structural genomics consortium, sgc, transferase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 70590.72

Authors

Chaikuad, A.,Zhubi, R.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2021-07-19, release date: 2022-04-13, Last modification date: 2024-01-31)

• Primary citation: Cullati, S.N.,Chaikuad, A.,Chen, J.S.,Gebel, J.,Tesmer, L.,Zhubi, R.,Navarrete-Perea, J.,Guillen, R.X.,Gygi, S.P.,Hummer, G.,Dotsch, V.,Knapp, S.,Gould, K.L.; Kinase domain autophosphorylation rewires the activity and substrate specificity of CK1 enzymes.; Mol.Cell, 82:2006-, 2022; PubMed: 35353987; DOI: 10.1016/j.molcel.2022.03.005

Experimental method

X-RAY DIFFRACTION (1.7 Å)