7P4L

Crystal structure of the trimeric ectodomain of archaeal Fusexin1 (Fsx1)

Summary for 7P4L

Entry DOI	10.2210/pdb7p4l/pdb
Related	1RER 4GSX 4OJC 6E18 6EGU
Descriptor	Fusexin1, CALCIUM ION, SODIUM ION, ... (5 entities in total)
Functional Keywords	fusexin, class ii fusion protein, membrane fusion protein, cell surface, membrane protein
Biological source	metagenome
Total number of polymer chains	3
Total formula weight	173082.91
Authors	Nishio, S.,Tunyasuvunakool, K.,Jumper, J.,De Sanctis, D.,Jovine, L. (deposition date: 2021-07-12, release date: 2022-07-13, Last modification date: 2024-03-27)
Primary citation	Moi, D.,Nishio, S.,Li, X.,Valansi, C.,Langleib, M.,Brukman, N.G.,Flyak, K.,Dessimoz, C.,de Sanctis, D.,Tunyasuvunakool, K.,Jumper, J.,Grana, M.,Romero, H.,Aguilar, P.S.,Jovine, L.,Podbilewicz, B. Discovery of archaeal fusexins homologous to eukaryotic HAP2/GCS1 gamete fusion proteins. Nat Commun, 13:3880-3880, 2022 Cited by PubMed: 35794124 DOI: 10.1038/s41467-022-31564-1 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation